The animal model summaries and descriptions have been curated by the National Institutes of Health (NIH) Accelerating COVID-19 Therapeutic Interventions and Vaccines (ACTIV) Preclinical Working Group with support from the Foundation for the National Institutes of Health (FNIH). New and updated information, including detailed individual animal model pages, will be provided as more scientific studies are shared. Please continue to check back for more information.
Feedback may be sent to ACTIVpreclinical@fnih.org.


Small Animals

Species Modification Model Name/Nomenclature
Vaccines
Antivirals
Neutralizing Antibodies
Other Therapies
Infectivity
Transmission
Disease Enhancement
Disease Manifestation & Pathology Extent of disease
Updated:



Non-Human Primates

Species Geographic Origin Route of Exposure
Vaccines
Antivirals
Neutralizing Antibodies
Other Therapies
Infectivity
Transmission
Disease Enhancement
Disease Manifestation & Pathology Extent of disease
Updated:


= The model can be used to evaluate the noted agent type.
Y = Yes
N = No
TBD = *To be determined (TBD) entries indicate those for which there is either in progress relevant research studies or an absence of data in the current literature.
Other Therapies = Includes immunomodulators.